The FDA added a boxed warning to capecitabine and 5-FU labels, noting the risk of serious adverse reactions or death in patients with complete DPD deficiency. Capecitabine and 5-FU are both nucleoside ...
“The patient’s symptoms resolved after permanently stopping 5-FU and administering lactulose and intravenous fluids, therefore supporting the diagnosis of hyperammonemic encephalopathy due to 5-FU.” ...