Stress to a cell can trigger the activation of a specialized group of mitogen-activated protein kinase (MAPK) cascades that induce cell death (Karin and Delhase, 1998). Apoptosis signaling kinase 1 ...
ASK1 induces apoptosis in a variety of cells such as mink lung epithelial cells. 11 In cells of the nervous system, rat primary sympathetic neurones and NGF-treated rat pheochromocytoma, PC12 cells ...