In a recent study posted to the bioRxiv* pre-print server, researchers investigated allosteric binders of angiotensin-converting enzyme 2 (ACE2) that significantly inhibit severe acute respiratory ...
Scientists have discovered a new generation of angiotensin receptor blockers that may be used to treat coronavirus disease 2019 (COVID-19). In silico docking and molecular dynamics studies have shown ...
Role of the RAAS in the Pathophysiology of Heart Failure ACE inhibitors have no effect on angiotensin II formed by alternate pathways. In contrast, ARBs would be expected to inhibit the biologic ...
Patients with albuminuric chronic kidney disease without diabetes can experience a significantly increased survival free of kidney failure if treated with the combination of angiotensin receptor ...
Loss of ACE2, the protein used by the novel coronavirus to invade human cells, leads to an imbalance in systems that regulate essential metabolic functions, impairing blood filtration and causing ...
Perindopril reduced the primary end point of CVR disease, MI, and cardiac arrest by 20% (p=0.0003). Moreover, the rate of fatal and nonfatal MI was reduced by 24% (p=0.001). The primary end point ...
Humanwell Healthcare (Group) Co. Ltd. has described fused ring compounds acting as angiotensin AT2 receptor (AGTR2) agonists reported to be useful for the treatment of disorders of the ovary and ...
STOCKHOLM, SE / ACCESS Newswire / November 3, 2025 / Vicore Pharma Holding (STO:VICO) - Stockholm, November 3, 2025 - Vicore Pharma Holding AB (publ)(STO:VICO), unlocking the potential of a novel ...
Nothing has helped advance Dr. Onuigbo’s cause as much as the ONTARGET findings (N Eng J Med. 2008:358:1547-1559).The study showed that a combination of telmisartan and ramipril reduces proteinuria to ...
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