A non-monotonic force–velocity relationship in cardiac sarcomeres causes dynamic instability, leading to stochastic heterogeneity in contracting cardiomyocytes, which can have a protective function.

Researchers have successfully developed a realistic theoretical model that provides a rational explanation for the spontaneous oscillatory contraction (SPOC) of muscle. The findings were published in ...

When muscle cells are viewed under the microscope, one can see that they contain a striped pattern (striations). This pattern is formed by a series of basic units called sarcomeres that are arranged ...