Eukaryotic cells initiate DNA replication from multiple origins, which must be tightly regulated to promote precise genome duplication in every cell cycle. To accomplish this, initiation is ...
Figure 1: Mis4 Scc2 –Ssl3 Scc4 is a DNA-binding protein. Taking these properties into account, we devised an assay to detect topological cohesin loading onto DNA (Fig. 2c). Cohesin and a relaxed ...
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