< Photo 1. (From left) Professor Won Do Heo and Jihwan Yu, a Ph.D. Candidate of the Department of Biological Sciences > CRISPR-Cas13, a powerful RNA-targeting technology is gaining increasing ...

Once considered passive messengers of genetic information, RNA molecules are now understood to play an active and dynamic role in gene regulation, modulated by a rich layer of chemical modifications ...

Researchers from the University of Eastern Finland and Aalto University have developed a computational framework called SegPore that enhances the accuracy of RNA modification detection from direct RNA ...

RNA plays critical roles in nearly all biological processes, but current methods for sequencing RNA are significantly limited. This is partially because RNA molecules are chemically modified within ...

CRISPR-Cas13, a powerful RNA-targeting technology is gaining increasing attention as a next-generation gene therapy platform due to its precision and reduced side effects. Utilizing this system, ...

Researchers have developed a powerful tool capable of scanning thousands of biological samples to detect transfer ribonucleic acid (tRNA) modifications—tiny chemical changes to RNA molecules that help ...

Cells contain a blueprint in the form of DNA that dictates what they can make. This blueprint is converted into a message, or mRNA, which is then converted into protein. Although DNA remains the same ...

A chemical modification in the HIV-1 RNA genome whose function has been a matter of scientific debate is now confirmed to be key to the virus's ability to survive and thrive after infecting host cells ...

This image depicts the chemical structure of cytosine. It shows a hexagonal ring with nitrogen atoms at positions 1 and 3, and a primary amine group attached to carbon 4. The two remaining positions ...

A new liquid biopsy developed by researchers at the University of Chicago is offering a powerful new window into cancer’s earliest stages by flagging subtle shifts in the gut microbiome. Unlike ...