32 P-label is introduced by incoming dGT 32 P molecule. The arrows indicate the sites of enzymatic hydrolysis. The bases of the template DNA strand are designated as clear boxes, and the bases in the ...

The discovery of DNA structure by James Watson and Francis Crick in the year 1953 is one of the most revolutionary scientific discoveries to date. However, the research leading to the discovery of ...

A new study published in Nature Structural & Molecular Biology reveals how the fundamental enzyme called DNA polymerase delta operates during DNA replication, making a copy of the genetic code that ...

DNA sequences with the potential to form unusual conformations, which are frequently associated with cancer and neurological diseases, can in fact slow down or speed up the DNA synthesis process and ...

Hailin Wang, Meiling Lu, Moon-Shong Tang, Bennett van Houten, J. B. Alexander Ross, Michael Weinfeld, X. Chris Le, Philip C. Hanawalt Proceedings of the National ...

DNA ligase D (LigD) is a large polyfunctional protein that participates in a recently discovered pathway of nonhomologous endjoining in bacteria. LigD consists of an ATP-dependent ligase domain fused ...