Fig. 4: The process of establishment of pre-RCs at an S. cerevisiae origin in which the B2 domain is separated from the A and B1 origin elements. This Review focuses on the first step in eukaryotic ...
Replication stress (RS) is a major source of genomic instability and is intrinsic to cancer cells. RS is also the consequence of chemotherapeutic drugs for treating cancer. However, adaptation to RS ...
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