Down Syndrome, known as Trisomy 21, is a genetic disorder caused by an extra chromosome 21. It affects facial appearance, ...

Most commonly, trisomy 21 arises because of meiotic nondisjunction in which ... An international consortium of brain banks—the Down Syndrome Biobank Consortium—has been established to collect and ...

FOR TOO long, Black children with Down syndrome (Trisomy 21) have been invisible, absent from mainstream representation, ...

Gene editing techniques may eventually allow trisomy to be treated at the cellular level, according to an in vitro proof-of-concept study.

The brain of a US woman with Down syndrome showed the classic signs of Alzheimer’s disease upon her death, yet she remained ...

Pathfinder Village will hold a series of in-person and virtual events leading up to World Down Syndrome Day on Friday, March 21. According to a Pathfinder news release, the activities "are focused on ...

Down syndrome is caused by the presence of a third ... system to cleave the third chromosome in previously generated trisomy 21 cell lines derived from both pluripotent cells and skin fibroblasts.

Gene editing techniques may eventually allow for trisomy disorders to be treated at the cellular level, according to an in ...

Down syndrome is caused by the presence of a third ... specific multiple chromosome cleavage using CRISPR-Cas9 in trisomy 21 cells, PNAS Nexus (2025). DOI: 10.1093/pnasnexus/pgaf022 ...