A University of Minnesota Medical School-led research team has discovered that a cancer signaling pathway has previously ...

Researchers have uncovered a surprising connection between a cancer-related signaling pathway and the blood-brain and blood-retina barriers.

This pathway is known to be involved in detoxification of environmental dioxin-related substances, and closely linked to hypoxia/normoxia signaling, but also parts of it are crucially involved in ...

The innate immune response is the body's first line of defense against infection, and a successful immune defense takes a ...

Neural activity in healthy brain releases glutamate which binds to synaptic receptors and activates Ca ++ influx and further signaling pathways of CAM/ERK/MAPK/CREB in neurons. CREB elevation ...

c-Fos exhibits a dual role: supporting memory in healthy brains and driving neurodegeneration in AD. Its dysregulation in AD involves multiple pathways, including Aβ toxicity, apoptosis, and ...

By creating artificial aging in mice, researchers at Lund University in Sweden have been able to track the formation of ...

Research has identified the first inter-species signaling pathway between an arthropod parasite and host, where molecules in the blood of a host animal triggers the immunity and development of a ...

Notch signaling, a key biological pathway tied to development and cell communication, also plays an important role in the onset of obesity and type 2 diabetes, a discovery that offers new targets ...

The Wnt pathway plays a wide variety of roles in animal and human development, and the ability to regulate it with light will allow researchers to better study its assorted functions.

These interactions play a vital role in modulating complex signaling pathways that control various cellular processes, such as cell growth, differentiation, and response to environmental stimuli.