G protein-coupled receptors (GPCRs) are expressed on the surface of cells and regulate a range of important functions. Because they are involved in so many sensory and physiological processes, ...
A number of membrane proteins that are present on the cell membrane control external and internal material transportation, cell protection and signal transmission. The diversity of functions of ...
A GPS-like technique has been used to track G protein-coupled receptor movement, revealing how these essential receptors function. Although G protein-coupled receptors (GPCRs) are crucial to the ...
GPCRs are the largest receptor class, affecting almost every aspect of human physiology, with 35% of all approved drugs acting on GPCRs. They regulate sensory and neuronal signaling, as well as a ...
Researchers have shown that tolvaptan, an existing kidney medicine, can stabilise nearly all mutated variants of a critical ...
Researchers at Leipzig University and Martin Luther University Halle-Wittenberg have investigated a previously unknown ...
GLP-1 is a natural human hormone that regulates blood glucose levels. Scientists have now created long-lasting GLP-1 drugs ...
From bispecific engineering to clinically relevant data sourcing, evolving antibody technologies advance oncology therapeutics.
From September 1, 2021, to March 23, 2022, 33 patients were infused with anti-GPRC5D CAR T cells. At a median follow-up of 5.2 months (range, 3.2‐8.9), the overall response rate was 91% (95% CI, 76 to ...
AbbVie is paying $255 million cash to acquire British biotech DJS Antibodies and its platform for targeting transmembrane proteins. DJS is focused on difficult-to-drug disease-causing proteins, such ...
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