Much of the phenotypic variation that is observed within and between species is the result of differences in gene regulation: specifically when, where and how much the genes are expressed. Given the ...

Torino is a computational workflow that uses biobank-scale RNA-seq data to decode transcript structures and expression levels from read coverage alone.

A research team has identified the core gene expression networks regulated by key proteins that fundamentally drive phenomena such as cancer development, metastasis, tissue differentiation from stem ...

In biology classrooms, we often learn that genes are transcribed into mRNA, which is then translated into proteins—a tidy, linear process. But gene expression in living cells is far more intricate, ...

Epigenetics is the study of various heritable alterations that control gene expression without changing the DNA sequence. 1 The name epigenetics comes from the Greek prefix “epi”, which means on top ...

RNA-binding proteins (RBPs) are central regulators of post-transcriptional gene expression. They modulate key aspects of mRNA metabolism—such as splicing, ...

Researchers from the National University of Singapore (NUS) have revealed that diet and exercise can change gene regulation in the skeletal muscle of East Asians, highlighting the critical role of ...

Biological rhythms aren't just for sleep. In the tiny worm C. elegans, researchers in the Grosshans lab and the Computational ...

New work shows that physical folding of the genome to control genes located far away may have been an early evolutionary ...

Elderberry juice intake triggers metabolic gene expression changes, enhancing glucose control and fat oxidation in overweight ...