A 'loopy' discovery in bacteria is raising fundamental questions about the makeup of our own genome -- and revealing a potential wellspring of material for new genetic therapies. A "loopy" discovery ...

From the completion of the pilot phase of The ENCODE Project in 2007, it has been evident that there is much more to a gene than the just a sequence that codes for protein, changing our concept of ...

In three back-to-back papers and five pages of the April 25, 1953, issue of Nature, seven authors laid out the evidence and interpretation that established the double helical structure of DNA. As ever ...

A reduced genome in an island species raises evolutionary questions.

DNA-encoded chemical libraries (DELs) have emerged as a transformative technology in drug discovery, offering unparalleled efficiency in the identification of bioactive small molecules. By covalently ...

It has been claimed that because most of our DNA is active, it must be important, but now human-plant hybrid cells have been ...

Nowadays, there's lots of buzz about spectacular new medical treatments such as personalised cancer therapy with modified immune cells or antibodies. Such treatments, however, are very complex and ...

Harvard scientists successfully recorded five frames of Eadweard Muybridge's 1887 galloping horse on living bacteria, and retrieved the images in sequence. When harnessed, this system has the ...

Management of mitochondrial-related heart disease relies on multidisciplinary care and symptom control, as targeted gene-editing therapies are limited.

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