The buildup of uric acid in your joints can lead to swollen growths under your skin called tophi. If left untreated, tophi can lead to loss of motion in your joints and other complications. A tophus ...

This study demonstrates that gout patients from the US and three EU countries suffer from significantly decreased HRQOL, with the average patient suffering decreased mental as well as physical ...

gout of foot The investigational drug AR882 appeared more effective and safer than allopurinol monotherapy in a phase 2 trial. A novel selective URAT1 inhibitor, AR882, further reduces serum uric acid ...

Krystexxa, a PEGylated uric acid specific enzyme, is approved for the treatment of refractory chronic gout. One study retrospectively analyzed data from two 6-month, randomized clinical trials that ...

Bone erosions, which are associated with long-term damage and disability, are common in patients with gout and have been linked with specific clinical and ultrasound-detected factors, Chinese ...

SAN DIEGO, Aug. 20, 2025 /PRNewswire/ -- Arthrosi Therapeutics, Inc., a late-stage biotechnology company advancing a potentially best-in-class, highly potent and selective next generation URAT1 ...

kidney cross section Researchers assessed the incidence and potential risk factors for the development of fenofibrate-associated nephrotoxicity in patients with gout. Fenofibrate-associated ...

The characteristics of the sample are presented in Table 1 and Table 2. The average age was 60.9 years, and patients had been diagnosed an average of 12 years. Most were male (81%), and 38% were ...