Oestrogen-induced DNA damage drives genomic instability in BRCA1 mutation cells, with dietary compounds showing protective potential.

Induced mutagenesis has emerged as a pivotal tool in plant biology, enabling the deliberate generation of genetic variation to elucidate gene function and drive crop improvement. By employing chemical ...

The first systematic whole genome sequencing study of how chemotherapy damages healthy tissues has shown that many, but not all, of these agents cause mutations and premature aging of normal blood ...

Climate change is impacting food production globally. With an ever-increasing global population and changing diets, the demand for pulses and grain legumes is rising swiftly. In the mixed and agro- ...

Scientists at Sanford Burnham Prebys Medical Discovery Institute and an international team of collaborators have defined a ...

KRAS mutated endothelium promotes the occurrence and development of AVMs through a variety of ways, including promoting EndMT, angiogenesis, VEGF signaling pathway and pericyte loss. KRAS mutation in ...

A therapy that targets a mutation in a critical tumor suppressor gene exhibited “impressive” activity in a cohort of heavily ...

A long-running experiment in serial mouse cloning has produced a sharp scientific reversal. A 2013 peer-reviewed report ...