Delve into Vandria's technology and its Alzheimer's candidate, VNA-318, the first mitophagy-based candidate in Alzheimer's in ...

Accumulation of damaged mitochondria in neurons is a hallmark of neurodegenerative disorders including Alzheimer disease (AD). A new study in Nature Neuroscience reports impaired mitophagy — the ...

“[...] our current work has provided a novel strategy to enrich for a sub-population of cancer cells, with high basal levels of mitophagy.” Mitophagy is a ...

RAB27A-dependent mitochondrial recruitment of SYTL5 promotes mitophagy and mitochondrial bioenergetics upon hypoxia.

Damaged mitochondria can be eliminated from the cell by the PINK1-Parkin mitophagy pathway, but whether there is a convergent ...

Mitophagy is a selective form of autophagy via which the damaged mitochondria are cleared via the autophagy-lysosome pathway. Mitophagy is an essential part of mitochondrial quality control and plays ...

After sparking further interest from investors after the close of its series A, Vandria SA has extended the round and now has the means to advance its lead mitophagy inducer program as far as phase Ib ...

A team of cell biologists from the Max Perutz Labs at the University of Vienna has identified a previously unrecognised pathway that activates mitophagy, a process in which damaged mitochondria are ...

Lifespan and pathway engineering in yeast raised sclareol output and strengthened production of other metabolites, enabling ...