The separation of enantiomers – mirror-image forms of chiral compounds – is a pivotal process in chemical research due to its wide-reaching applications in pharmaceuticals, agrochemicals and materials ...

Early in the drug discovery process, it is necessary to begin studies on enantiomerically pure compounds due to the potential for unique efficacy and adverse effects associated with one enantiomer ...

Researchers have developed a highly efficient way to produce chiral multi-centered fused tricyclic compounds of which core structure is often found in bioactive compounds including medicines. Osaka ...

Chemists from the National University of Singapore (NUS) have conceived a strategy using chiral nickel catalysts to facilitate the carboboration of alkenes, generating high-value enantioenriched ...

Atropisomers are a class of stereoisomers (chemical compounds that differ in spatial arrangement of atoms) arising from restricted rotation around a single bond and have various applications in ...

The preparation of chiral compounds as intermediates in drug synthesis is one of the most important targets in synthetic organic chemistry. Japanese scientists have now shown that the autocatalytic ...

A Hong Kong University of Science and Technology (HKUST) research team has developed a catalytic enantioselective type II [5 + 2] cycloaddition method to address the challenges of synthesizing chiral ...

The latest short science news items from C&EN. “Most people don’t think about an amine being chiral because it rapidly interconverts,” Kitching says. The lone electron pair that gives amines their ...

Electrons in ''chiral crystals'', solid-state materials with definite ''handedness'', can behave in unexpected ways. An interdisciplinary team has realized now a theoretically predicted peculiar ...

Many chemical molecules can exist in nature together with their mirror counterparts; like hands, two compounds can be made up of the same atoms in the same overall structure but in opposite ...

Like carbon and silicon, germanium’s lighter brethren on the periodic table, the metalloid can bond to four different groups, forming a chiral, tetrahedral molecule. Researchers at Nankai University ...