G protein–coupled receptors (GPCRs) play crucial roles in the regulation of a wide variety of physiological processes and represent one-third of targets with clinically prescribed drugs. Yet, it ...
Immune-mediated inflammatory diseases (IMIDs) are a heterogeneous group of diseases characterized by chronic inflammation and organ damage. IMIDs were traditionally classified on the basis of the ...
Expert Rev Mol Diagn. 2009;9(2):139-156. Diagnosis AIH-score > 15 AMA-M2 Elevated aP/γ-GT Compatible histology Cholangiography Elevated aP/γ-GT pANCA IBD γ-GT = γ-glutamyl transferase; AIH = ...
Redefining Allergy Treatment with New Class of Trifunctional ECRIs designed to deliver powerful efficacy, rapid relief and complete control of ...
Excellergy has emerged with $70 million and an investigative drug class in its portfolio, part of its ambitious mission to ...
Excellergy is developing medicines that combat allergic responses in three different ways, a multipronged effect the company ...
A collaborative study on a plant intracellular immune receptor not only shows how an important resistance protein is activated during pathogen infection but also reveals some common operational ...
Pre-clinical data supports ECRIs' broad-spectrum attack on the IgE axis, distinct from conventional anti-IgE therapies, ...
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