Systemic sclerosis (SSc) is a severe autoimmune disease with complex genetic causes. Some genetic contributors have been identified, but others remain unknown, which has impeded development of ...

Long-read sequencing technologies analyze long, continuous stretches of DNA. These methods have the potential to improve researchers' ability to detect complex genetic alterations in cancer genomes.

Illumina DNA sequencing machines are vulnerable to exploitation. Both the Cybersecurity and Infrastructure Security Agency (CISA) and the Food and Drug Administration (FDA) have published advisories ...

At an old biscuit factory in South London, giant mixers and industrial ovens have been replaced by robotic arms, incubators, and DNA sequencing machines. James Field and his company LabGenius aren’t ...

What is Nanopore DNA Sequencing? Nanopore DNA sequencing is a cutting-edge technology that enables the direct, real-time analysis of long DNA or RNA fragments. Unlike conventional sequencing methods ...

A U.K. program—similar to one launched in New York last fall— will begin genome sequencing on 100,000 babies this year to figure out whether screening newborns for a wide range of conditions is ...

In the 1990s, the Human Genome Project (HGP), which aimed to map the entire ~3 billion base pairs of the human genome, clearly demonstrated the technical challenges underlying the measurement of many ...

A fundamental challenge in mass spectrometry-based proteomics is the identification of the peptide that generated each acquired tandem mass spectrum. Approaches that leverage known peptide sequence ...

SAVANA uses a machine learning algorithm to identify cancer-specific structural variations and copy number aberrations in long-read DNA sequencing data. The complex structure of cancer genomes means ...

Scientists at the Baylor College of Medicine and collaborating institutions used complementary approaches that integrate exome sequencing and evolutionary action machine learning to identify protein ...