In protein synthesis, elongation factor G (EF-G) facilitates movement of tRNA–mRNA by one codon, which is coupled to the ratchet-like rotation of the ribosome complex and is triggered by EF-G–mediated ...

Having solved the first crystal structure of a eukaryotic ribosome, scientists are now getting a new, more detailed look at the machinery that translates the genetic code into proteins in all living ...

A new study finds that RNA, considered the DNA template for protein translation, often appears with an extra letter -- and this letter is the regulatory key for control of gene expression. The ...

In the fast-evolving field of medical science, a new artificial intelligence model may be about to change the way mRNA-based drugs and vaccines are designed. Developed through a collaboration between ...

RNA is a single stranded molecule containing a ribose sugar. It has a distinctive structure and, unlike DNA, there are variations and various types of RNA structures. A base is attached to the 1' ...

All three RNAPs have catalytic cores consisting of 10 subunits. Five of these are core subunits which form crab claw shapes with DNA at their centres, channels for RNA products and NTP substrates as ...

Japan biotech xFOREST Therapeutics is teaming up with a drug discovery solutions provider in a research pact aiming to develop new RNA structure-targeted small molecule therapeutics, including mRNA ...

DNA, RNA, protein -- the end. Or is it? Until recently, the pattern used to encode genetic information into our cells was considered to be relatively straightforward: four letters (A,G,C,T) for DNA ...