I qualified from UCL Medical School in 2019 with Distinction in Medical Sciences. En route, I completed a Neuroscience BSc at UCL in 2016 with First Class Honours and Dean's List Commendation. After ...

Blood tests for Alzheimer’s disease are rapidly transforming the way clinicians diagnose the disease. Still, some scientists urge caution when interpreting results, arguing that the meaning of a ...

Rarely do scientists discover a new pathogenic mutation for a sporadic disease. Even less often do they find one that explains half the cases. Pinning disease on a dinucleotide expansion? That’s a new ...

Comments Meet Tanycytes: Bridging Brain and Body, These Cells May Dispose of Tau 13 Mar 2026 ...

Scientists continue to look for new ways to target sticky amyloid plaques in the brain. The approved immunotherapies have well-known limitations. In the March 5 Science, Marco Colonna and colleagues ...

Tau made in the brain eventually shows up in blood, but scientists still aren’t sure how it gets there. Now, research featured in Cell Press Blue offers a new idea. This journal launched in January to ...

The MCI-Park mice are compound mutant (Ndufs2fl/fl; DAT IREScre/+) animals in which Ndufs2, a gene encoding a core subunit of the mitochondrial respiratory chain, is selectively inactivated in ...

Circular RNAs are the byproducts of aberrant “backsplicing.” They accumulate and cause problems in the brain with age. According to a study published March 5 in Molecular Cell, ribonuclease κ—an ...

An interactive timeline of the evolution of Alzheimer's Disease research.

The gene PSEN2 encodes presenilin-2, a subunit of γ-secretase, the aspartyl protease responsible for Aβ generation. Missense mutations in PSEN2 are a rare cause of early onset Alzheimer's disease.

Jiang R, Zheng X, Sun J, Chen L, Xu G, Zhang R. Classification for Alzheimer's disease and frontotemporal dementia via resting-state electroencephalography-based coherence and convolutional neural ...

At a young age, this transgenic mouse develops severe motor impairment and other ALS-related phenotypes. Notably, it develops robust neuronal loss in the spinal cord, denervation of neuromuscular ...