It has been suggested that differences in mouse and human tau may partially underlie the difficulty in modeling Alzheimer’s disease in mice (see Alzforum webinar). In this knock-in model, the entire ...
I qualified from UCL Medical School in 2019 with Distinction in Medical Sciences. En route, I completed a Neuroscience BSc at UCL in 2016 with First Class Honours and Dean's List Commendation. After ...
As the brain’s jumpy immune responders, microglia have the potential to ward off AD pathogenesis … or make it worse. On which side of this fine line they fall seems to change as disease progresses, ...
The MCI-Park mice are compound mutant (Ndufs2fl/fl; DAT IREScre/+) animals in which Ndufs2, a gene encoding a core subunit of the mitochondrial respiratory chain, is selectively inactivated in ...
An interactive timeline of the evolution of Alzheimer's Disease research.
We have developed this special section of the Alzforum website to provide a resource for all who share an intense interest in familial early onset AD (eFAD). We have created this series of articles ...
Sensory Stimulation Systems, and GENUS, refer to a noninvasive procedure, i.e., a "digital therapeutic," being developed by Cognito Therapeutics. The company developed a wearable GammaSense ...
Jiang R, Zheng X, Sun J, Chen L, Xu G, Zhang R. Classification for Alzheimer's disease and frontotemporal dementia via resting-state electroencephalography-based coherence and convolutional neural ...
At a young age, this transgenic mouse develops severe motor impairment and other ALS-related phenotypes. Notably, it develops robust neuronal loss in the spinal cord, denervation of neuromuscular ...
Dept. of Geriatrics/Memory Disorders Unit Block 85, 7th floor 751 85Uppsala Sweden Visit Website ...
Score another one for amyloid immunotherapy. The anti-pyroglutamated amyloid antibody donanemab has posted positive top-line results in the Phase 3 Trailblazer-Alz2 study, according to an Eli Lilly ...
The Alzheimer’s field was rocked this week by allegations against Sylvain Lesné at the University of Minnesota, Minneapolis. Lesné stands accused of manipulating data images in multiple papers, ...