Chronic inflammation is both a driver and suppressor of cancer depending on context. Key players-NF-κB, IL-6, STAT3, TAMs, MDSCs, and Tregs-orchestrate a tumor-permissive microenvironment.

Our past experiences shape how much we eat and where and what we choose to eat. Using preclinical models, researchers from Mass General Brigham and the Broad Institute of MIT and Harvard have ...

Precise coordination of cell growth and cell-cycle progression is essential for maintaining tissue integrity and organismal health. When these regulatory ...