EM, biochemical, and cell-based assays to examine how Gβγ interacts with and potentiates PLCβ3. The authors present evidence for multiple Gβγ interaction surfaces and argue that Gβγ primarily enhances ...

The next surprise was that human organoids just kept growing. Mouse organoids were done with making neurons within nine days.

A burgeoning field is launching its first clinical trial to find out whether dialling back cell development can safely ...

BACKGROUND: Despite antiplatelet therapy, some patients remain at high ischemic risk because of drug nonresponsiveness or high residual platelet reactivity). We aimed to target an orphan platelet GPCR ...