Neural activity in healthy brain releases glutamate which binds to synaptic receptors and activates Ca ++ influx and further signaling pathways of CAM/ERK/MAPK/CREB in neurons. CREB elevation ...

c-Fos exhibits a dual role: supporting memory in healthy brains and driving neurodegeneration in AD. Its dysregulation in AD involves multiple pathways, including Aβ toxicity, apoptosis, and ...

After reports and rumors of the NBA Draft’s No. 5 pick have swirled both pre and post draft, the former Rutgers star is on his way to Utah to report to the Jazz and get to work.

A University of Minnesota Medical School-led research team has discovered that a cancer signaling pathway has previously ...

Researchers have uncovered a surprising connection between a cancer-related signaling pathway and the blood-brain and blood-retina barriers.

Estrogen plays an important role in keeping bones healthy. Now, researchers investigated how membrane-initiated estrogen ...

By creating artificial aging in mice, researchers at Lund University in Sweden have been able to track the formation of ...

Heterogeneous Hippo pathway (YAP/TAZ) activation in lung adenocarcinoma drives tumor progression by enabling ferroptosis ...

BACKGROUND: Direct reprogramming of fibroblasts to cardiomyocytes is a potentially curative strategy for ischemic heart ...

Although commitment of mesenchyme precursors to the osteochondrogenic lineages requires both Wnt and bone morphogenetic protein signaling, the canonical Wnt pathway subsequently acts as the master ...

There are two major signalling pathways that lead to apoptosis in mammalian cells: the intrinsic pathway and the extrinsic pathway.

Growth factor signalling is a cell signalling pathway that regulates the growth and development of an organism. Secreted growth factors bind to transmembrane growth factor receptors to stimulate ...