New research has identified the gene Egr-1 as a critical regulator of immune balance, offering hope for autoimmune disease therapies.

Estrogen plays an important role in keeping bones healthy. Now, researchers investigated how membrane-initiated estrogen ...

Plant phototropism—directional growth in response to light—serves as a key adaptive mechanism, optimizing photosynthesis and ...

Dopamine doesn’t flood the brain as once believed – it fires in exact, ultra-fast bursts that target specific neurons. The ...

Human respiratory syncytial virus viroporin SH: a viral recognition pathway used by the host to signal inflammasome activation ...

The metabolism of bone tumors is extraordinarily complex and involves many signaling pathways and processes, including the tumor necrosis factor (TNF) signaling pathway, which consists of TNF factors ...

Exposure to di- (2-ethylhexyl) phthalate reduces secretion of GDNF via interfering with estrogen pathway and downregulating ERK/c-fos signaling pathway in astrocytes.

Ginsenoside RK1 Promotes Hepatic Stellate Cell Glycolysis-Mediated Ferroptosis by Activating the HK2/ACSL4/LPCAT3/ALOX5 Signaling Pathway ...

Although commitment of mesenchyme precursors to the osteochondrogenic lineages requires both Wnt and bone morphogenetic protein signaling, the canonical Wnt pathway subsequently acts as the master ...

c-Fos exhibits a dual role: supporting memory in healthy brains and driving neurodegeneration in AD. Its dysregulation in AD involves multiple pathways, including Aβ toxicity, apoptosis, and ...

Neural activity in healthy brain releases glutamate which binds to synaptic receptors and activates Ca ++ influx and further signaling pathways of CAM/ERK/MAPK/CREB in neurons. CREB elevation ...