Aidan O’Brien’s Betfred 2000 Guineas hope Twain has been declared a major doubt for Saturday’s opening Classic of the season at Newmarket.

The drug maker said it is ‘firmly committed to investing and growing in the US’ amid potential import tariffs on the pharmaceutical industry.

Daniel Graham and Adam Carruthers used a chainsaw to chop down the Northumberland landmark and filmed their ‘mindless vandalism’, a court heard.

Human rights laws could still be an obstacle to removing foreign sex offenders from the UK, the Home Secretary said, as she suggested changes could be needed to the way the rules are interpreted.

Yostin Andres Mosquera is accused of killing Albert Alfonso and Paul Longworth in London and dumping their remains near the Clifton ...

Play at the Madrid Open will resume as scheduled on Tuesday following Monday’s power cut. The outage, which affected much of Spain and Portugal, forced play to be suspended just after 12.30pm local ...