Aidan O’Brien’s Betfred 2000 Guineas hope Twain has been declared a major doubt for Saturday’s opening Classic of the season at Newmarket.

The drug maker said it is ‘firmly committed to investing and growing in the US’ amid potential import tariffs on the pharmaceutical industry.

Daniel Graham and Adam Carruthers used a chainsaw to chop down the Northumberland landmark and filmed their ‘mindless vandalism’, a court heard.

Human rights laws could still be an obstacle to removing foreign sex offenders from the UK, the Home Secretary said, as she suggested changes could be needed to the way the rules are interpreted.

Yostin Andres Mosquera is accused of killing Albert Alfonso and Paul Longworth in London and dumping their remains near the Clifton ...

Play at the Madrid Open will resume as scheduled on Tuesday following Monday’s power cut. The outage, which affected much of Spain and Portugal, forced play to be suspended just after 12.30pm local ...

Kemi Badenoch has said she would not want a man performing an “intimate” examination which checks for breast cancer. The ...

The prevalence of dementia in football must be tackled by the sport’s new independent regulator, MPs have said. Members have called for the new watchdog to be given powers to investigate the issue or ...

Sir Stephen Houghton, chairman of the body representing metropolitan district councils, questioned benefits changes and investment strategy.

Nicholls has been champion trainer 14 times, so watching Willie Mullins and Dan Skelton fight it out for the title for the last two seasons has not sat well with the fiercely-comp ...

Prices were largely driven higher by a 17.4 rise in chocolate confectionery prices in the four weeks to April 20.

Thousands of UK travellers are trying to return home on Tuesday after being stranded overnight because of widespread power cuts in Portugal and Spain. Airports in both countries were disrupted by the ...