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  1. TAFRO Syndrome: A Disease Requiring Immediate Medical ...

    TAFRO syndrome was first described by Takai et al. in 2010 (1). They reported three cases of thrombocytopenia associated with a fever, anasarca, hepatosplenomegaly and reticulin …

  2. TAFRO syndrome - Wikipedia

    TAFRO syndrome is a rare human systemic disease. The name is formed from the initials of thrombocytopenia, anasarca, fever, reticulin fibrosis and organomegaly. [1][2][3] It was first …

  3. TAFRO Syndrome: Symptoms, Diagnosis, and Treatment Options

    Aug 2, 2025 · TAFRO syndrome is a rare, multi-system inflammatory disorder. It presents as a complex condition due to its diverse clinical manifestations. First described in 2010, the …

  4. TAFRO Syndrome: Guidance for Managing Patients Presenting ...

    Jun 8, 2024 · TAFRO syndrome is an inflammatory disorder of unknown etiology characterized by thrombocytopenia, anasarca, fever, reticulin fibrosis, renal insufficiency, and organomegaly.

  5. TAFRO syndrome - Orphanet

    A rare systemic disease characterized by acute or subacute onset of thrombocytopenia, anasarca (edema, pleural effusion, ascites), and systemic inflammation (fever and/or elevated C …

  6. TAFRO Syndrome – Rare Inflammatory Disorder Explained

    TAFRO syndrome is a rare subtype of Castleman disease involving thrombocytopenia, anasarca, fever, and organ enlargement. Learn diagnosis and treatment.

  7. Do you know TAFRO? | Blood | American Society of Hematology

    Nov 15, 2018 · Patients with TAFRO-like presentations may benefit from alternative iMCD treatments as suggested by the authors. CD is not a uniform entity. Some patients require less …

  8. The experience of diagnosis and treatment for TAFRO syndrome

    Sep 15, 2023 · Early identification, diagnosis and treatment of TAFRO syndrome are very importants. We retrospectively analysed 6 patients with TAFRO syndrome. Their clinical …

  9. Castleman disease and TAFRO syndrome - PMC

    TAFRO syndrome was reported in Japan in 2010. Because lymph node histology is similar in patients with TAFRO syndrome and Castleman disease, TAFRO syndrome is described as a …

  10. TAFRO Syndrome - PubMed

    TAFRO syndrome is a newly recognized variant of idiopathic multicentric Castleman disease (iMCD) that involves a constellation of syndromes: thrombocytopenia (T), anasarca (A), fever …